Scientific Innovation

The Science Behind SDCC

Integrating the Elmourabea Logic with state-of-the-art Generative AI to decode the 4-letter language of DNA and transform predictive medicine.

Core Philosophy

Biology Meets Physics

Traditional oncology is reactive—waiting for physical mass. The Elmourabea System targets the "Maturation Phase": the precise thermodynamic moment a healthy cell transitions to malignancy due to a spike in Potential Energy.

Thermodynamic Detection

Scans for Potential Energy (Entropy & Chaos), not just morphology

Logic-Based Analysis

Identifies "Logic Breaks" in the 4x4 DNA matrix (A, T, C, G)

Pre-Clinical Intervention

Detects disease before visible to human eye or standard imaging

The Elmourabea Matrix

A
Adenine
Logic 1
T
Thymine
Logic 2
C
Cytosine
Logic 3
G
Guanine
Logic 4

Cancer = Logic Break in the 4x4 stability matrix

AI Architecture

The Generative AI Stack

Treating biology as a language, using Google's Gemma foundation models to decode DNA, RNA, and proteins.

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C2S-Scale

27B

Parameter Transformer

Single-cell transcriptomics analysis to find "cold" tumors invisible to immune system.

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MedGemma 1.5

4B

Instruction-Tuned

Multimodal analysis of histopathology & radiology for non-invasive diagnostics.

⚗️

popEVE / BSM

123

Validated Genes

Evolutionary generative model predicting pathogenicity of DNA variants.

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Local Inference

UAE

Data Sovereignty

gemma.cpp quantized deployment ensures no cloud offloading.

Clinical Impact

Real-World Applications

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Hepatology

Non-Invasive Liver Disease Staging

Detecting the "Pre-Cirrhotic" State (F2/F3) without painful biopsies, enabling intervention before irreversible damage.

0.99
AUROC
F0-F4 Staging vs Biopsy
  • Replaces invasive needle biopsies
  • Critical for UAE's high MASLD burden
  • Enables early lifestyle interventions
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Oncology

Cold Tumor → Hot Tumor Conversion

Using C2S-Scale to identify immune-resistant "cold" tumors and engineer therapeutic synergies.

CK2 Inhibitor
Novel Discovery
Silmitasertib + IFN-γ Synergy
  • Amplifies MHC-I expression
  • Makes tumors visible to T-cells
  • AI-discovered, unreported mechanism
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tRNA Therapeutics (ENSURE Platform)

Beyond Detection: Molecular Repair

When the AI identifies a nonsense mutation (premature stop codon), we engineer programmable tRNA molecules to "read through" the broken code and restore protein function.

Target Population
30M
Patients with Stop Codon Diseases

Key Innovations

  • 1
    Suppressor tRNA Design
    Engineered Arg-TGA for nonsense mutations
  • 2
    Structural Optimization
    Maintaining cloverleaf integrity with m¹A/m⁵C modifications
  • 3
    AI-Guided Design
    AlphaFold 3 integration for structure prediction

Validated Performance

Benchmarked against global standards

Key Metrics

Sensitivity 98%
Specificity 96%
AUROC 0.99

Research Alignment

  • University College London (UCL)
  • Technion Israel / Novocure
  • ETH Zurich / Siemens
  • Broad Institute (MIT/Harvard)

Open Research Repository

Full technical implementation, protocols, and data available on GitHub for scientific transparency and collaboration.

View on GitHub